Who might own immunotherapies derived from treating a patient ?

cyberianpan

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This us a big win:

Doctors hail world first as woman’s advanced breast cancer is eradicated
Next, the doctors extracted immune cells known as tumour infiltrating lymphocytes, or TILs, from the tumour biopsies. These are cells from the patient’s immune system that have invaded the tumour in a bid to kill it, but which failed in the task by being either too weak or too few in number.

After growing billions of these immune cells in the lab, the researchers screened them to find which ones would most effectively find and destroy the woman’s cancer cells by recognising their abnormal proteins.

The doctors treated Perkins by injecting 80 billion of the carefully-selected immune cells into her body.
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But:
But Melcher points out that the therapy is complex and expensive and more importantly, requires doctors to find enough infiltrating immune cells in a patient’s tumour to make the treatment effective.
There clearly is the potential for discoveries from one patient's immune system, to apply more generally

However...this is quite complex work, and it is not clear to me that the public health system is set up to effectively further such research

Traditionally this type of capital expensive experimentation has been done by private drug companies

Issues of ownership of genetic material apply here, also the treatment as outlined above, is not amenable to say the FDA process, as it is likely contingent on tailoring the treatment to each patient

So...how can such research be brought forward ?

Cyp
 


bactrian

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Joined
May 11, 2004
Messages
1,264
This us a big win:

Doctors hail world first as woman’s advanced breast cancer is eradicated


But:


There clearly is the potential for discoveries from one patient's immune system, to apply more generally

However...this is quite complex work, and it is not clear to me that the public health system is set up to effectively further such research

Traditionally this type of capital expensive experimentation has been done by private drug companies

Issues of ownership of genetic material apply here, also the treatment as outlined above, is not amenable to say the FDA process, as it is likely contingent on tailoring the treatment to each patient

So...how can such research be brought forward ?

Cyp
The news that a person might be cured of cancer by using their own immune system(medically boosted) is astonishingly good news.

A company can patent and protect the method by which they refine and concentrate "immune cells" . It cost a lot of money to develop these technologies . Patent away.

However the "idea" of using concentrated "immune cells" cannot be patented. Another company can , and probably will, develop another process to concentrate "immune cells".

Bring on the competition!!!
 

redhead

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Joined
Jun 11, 2007
Messages
6,663
This us a big win:

Doctors hail world first as woman’s advanced breast cancer is eradicated


But:


There clearly is the potential for discoveries from one patient's immune system, to apply more generally

However...this is quite complex work, and it is not clear to me that the public health system is set up to effectively further such research

Traditionally this type of capital expensive experimentation has been done by private drug companies

Issues of ownership of genetic material apply here, also the treatment as outlined above, is not amenable to say the FDA process, as it is likely contingent on tailoring the treatment to each patient

So...how can such research be brought forward ?

Cyp
It's great that this has been successful, I know that experimental gene therapy was in the works over twenty years ago, good to see it finally making some headway.

As for ownership, I think that while the cells themselves cannot be patented, the process itself can be. If the drugs companies see a potential for profit, they will put more money into getting it up and running, which is a win-win situation for all involved.
 


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